The Muskogee campus offers upper-level and graduate courses in the areas of education, business, general studies, nursing, industrial management, as well as classes in other disciplines. Northeastern State opened the 27,700 square-foot facility on its 23-acre campus in 1993. In 2001, The Mike Synar Center, a monument to the vision of Mike Synar, former U.S. Congressman from the 2nd District of Oklahoma from 1979 to 1995, opened.